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Symbol
Name
ID

Cxcr4
C-X-C motif chemokine receptor 4
MGI:109563

Phenotype annotations related to nervous system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Stroke	Anorexia	Ataxia	Cranial nerve paralysis	Multifocal epileptiform discharges	Memory impairment	Reduced consciousness	Migraine	Peripheral neuropathy	Polyneuropathy
Disease(s) Associated with CXCR4
lymphoplasmacytic lymphoma

Mouse Phenotypes		nervous system phenotype	absent cerebellar foliation	abnormal cerebellum external granule cell layer morphology	thin external granule cell layer	abnormal dentate gyrus morphology	abnormal cerebral cortex morphology	abnormal cerebellum morphology	ectopic Purkinje cell	abnormal nervous system physiology
Availability	Mouse Genotype	nervous system phenotype	absent cerebellar foliation	abnormal cerebellum external granule cell layer morphology	thin external granule cell layer	abnormal dentate gyrus morphology	abnormal cerebral cortex morphology	abnormal cerebellum morphology	ectopic Purkinje cell	abnormal nervous system physiology
	Cxcr4^tm1Qma/Cxcr4^tm1Qma
	Cxcr4^tm1Tng/Cxcr4^tm1Tng	*
	Cxcr4^tm1Yzo/Cxcr4^tm1Yzo	*
	Cxcr4^tm3.1Yzo/Cxcr4^tm3.1Yzo
	Cxcr4^tm1Tng/Cxcr4^tm2Tng Tg(Tek-cre)12Flv/0 (conditional)	*

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23